Hyperproliferation markers in ear canal epidermis

João Daniel Caliman e Gurgel, Siqueira Barbosa Pereira, Adriana Leal Alves, Fernando Quintanilha Ribeiro
Brazilian Journal of Otorhinolaryngology  
most of the studies utilized external auditory canal epidermis as control sample to study external ear or middle ear cholesteatoma with immunohistochemical methods. There is a hyperproliferative antigen concentration, such as CK16, Ki-67 and PCNA, in the annulus tympanicus, adjacent meatus and tympanic regions, mainly in the lower areas.
pmid:20963355 fatcat:cf4kbxjvzzdujhrnrphuxcg2de