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Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity
2013
Current Genomics
Prior to the completion of the human genome project, the human genome was thought to have a greater number of genes as it seemed structurally and functionally more complex than other simpler organisms. This along with the belief of "one gene, one protein", were demonstrated to be incorrect. The inequality in the ratio of gene to protein formation gave rise to the theory of alternative splicing (AS). AS is a mechanism by which one gene gives rise to multiple protein products. Numerous databases
doi:10.2174/1389202911314030004
pmid:24179441
pmcid:PMC3664468
fatcat:h7pkjfvxezauznlx3dthpyf2ce