AnnoLnc: a web server for systematically annotating novel human lncRNAs

Mei Hou, Xing Tang, Feng Tian, Fangyuan Shi, Fenglin Liu, Ge Gao
<span title="2016-11-16">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4srzxifvfrdlhjhg3dimznkp7m" style="color: black;">BMC Genomics</a> </i> &nbsp;
Although the repertoire of human lncRNAs has rapidly expanded, their biological function and regulation remain largely elusive. Here, we present AnnoLnc (http://annolnc.cbi.pku.edu.cn), an online portal for systematically annotating newly identified human lncRNAs. AnnoLnc offers a full spectrum of annotations covering genomic location, RNA secondary structure, expression, transcriptional regulation, miRNA interaction, protein interaction, genetic association and evolution, as well as an
more &raquo; ... ion-based text summary and various intuitive figures to help biologists quickly grasp the essentials. In addition to an intuitive and mobile-friendly Web interactive design, AnnoLnc supports batch analysis and provides JSON-based Web Service APIs for programmatic analysis. To the best of our knowledge, AnnoLnc is the first web server to provide on-the-fly and systematic annotation for newly identified human lncRNAs. Some case studies have shown the power of AnnoLnc to inspire novel hypotheses. not peer-reviewed)
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12864-016-3287-9">doi:10.1186/s12864-016-3287-9</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27852242">pmid:27852242</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5112684/">pmcid:PMC5112684</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/65ai73ck5zf27dfmg56l3dqkpm">fatcat:65ai73ck5zf27dfmg56l3dqkpm</a> </span>
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