Coronary Artery Bypass Graft in Six Members of a Family: A Case Series

Kambiz Alizadeh, Majid Ghodsi, Maryam Mahdavi, Bita Zargaran, Roghaye Alavinejad, Masoomeh Tabari
2018 Journal of Cardio-Thoracic Medicine  
Abstract: Coronary artery disease (CAD) is a multifactorial problem. Although hyperlipidemia (HLP), diabetes (DM), and hypertension (HTN) are known as the familial and cardiac risk factors, CABG is rare in the several members of a family. We reported the six members of a family who presented with MI and/or advanced angina pectoris during the 6 years. CABG(Coronary artery bypass graft) considered for all patients due to involvement in main coronary arteries and clinical presentation. The
more » ... fraction (EF) was varied between 25% to 70%. Beating heart cardiopulmonary bypass (beating heart CPB) and off-pump were chosen as surgical method. The mean duration of surgery was about 4 hours. The only post-operative complication was deep wound infected in a young man who was smoker and drug abuser. According to family relationship of patients and the high effect of genetic penetration, we presume the gene influence to incidence CAD and potential to undergoing CABG, in members of a special family.
doi:10.22038/jctm.2018.30629.1157 doaj:a5782d4e22264f0093728709a7524bd4 fatcat:5lgml27zkjhybebbbznr7w3y24