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Characterization of the microbiome of Down syndrome mouse model (Ts65Dn) in standard and high-fat diet
[article]
2020
bioRxiv
pre-print
The intestinal microbiota is known to affect its host in numerous ways and can be altered by many factors including the host genotype and high-calorie diets. Down syndrome (DS) is a genetic neurodevelopmental disorder caused by the total or partial triplication of chromosome 21. Recently, a human study reported microbiota differences between DS and euploid humans. To further explore the differences due to the genotype, we here investigated the microbiome of trisomic mice (Ts65Dn). In trisomic
doi:10.1101/2020.11.16.385989
fatcat:lxlu53n7ibenng34myiwlcmzle