ブロイラーの筋胃びらんおよびかいよう III 魚粉中の毒性成分の検索
Gizzard Erosion and Ulceration in Broilers

Tadahiro MASUMURA, Hiroshi HORAGUCHI, Hiroshi HORIKAWA, Michihiro SUGAHARA
1981 Japanese poultry science  
It was reported that gizzard erosion and ulceration in broilers (GE) were caused by fish meal. In order to investigate toxic substance(s) in the fish meal incriminated for GE, several experiments were performed. A kind of fish meal, B-2, which caused GE after heat-treatment in the previous experiment, was extracted to get water-soluble extract. These experiments were conducted with 10 one-day-old broiler chicks each kept in battery brooders to feed the diets containing toxic substance(s) for 2
more » ... eeks. The results obtained are summarized as follows. (1) A mixture of the extract and casein, as well as egg albumin, caused GE at dry (2) An amino acid mixture, simulated to contain the same free amino acids in the extract, caused GE at dry heating with casein, as well as white fish meal. The casein. and the white fish meal, used in this experiment, caused no GE itself at dry heating. (3) A mixture of histidine hydrochloride and casein, as well as white fish meal, caused GE at dry heating. Severer GE was induced when the mixture was heated in acidic condition (pH 5.5) than in neutral condition (pH 6.5-7.5). (4) A mixture of histamine hydrochloride and casein, as well as the white fish meal, caused GE at dry heating. A mixture of histamine hydrochloride and white fish meal caused GE without heating. The severity of GE, however, apparently increased at dry heating. From these results, it was suggested that toxic substance(s) in the fish meal causing GE in broiler chicks might have been formed from free histidine and histamine by a reaction with protein in the fish meal at heating. (Japan. Poult. Sci., 18, 98-104, 1981)
doi:10.2141/jpsa.18.98 fatcat:5mwqtm5lkfcgpfmdwqsqbcmezm