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Prosthetic joint infection (PJI) due to Mycobacterium tuberculosis (MTB) without previous history of tuberculosis is an extremely rare complication. We report the case of an 80-year-old man, with no prior history of tuberculosis. The patient underwent replacement arthroplasty and the infection was successfully treated with combination of oral anti-tuberculous drugs for one year.doi:10.4172/2327-5073.1000114 fatcat:3e3d253ndzhtrhrehni5lftrwi