Multiple myeloma: five-year experience at a University Hospital

Juliana Todaro, Jandey Bigonha, Davimar Miranda Maciel Borducchi, Leandro Luongo Matos, Damila Cristina Trufelli, Suzane Martines Alves de Sales, Marina Rampazzo Del Valhe Shiroma, Auro del Giglio
2011 Einstein (São Paulo)  
Objective: To present a descriptive analysis of patients diagnosed with multiple myeloma, correlating it with mortality. Methods: A retrospective study that analyzed consecutive patients diagnosed with multiple myeloma under follow-up at the Faculdade de Medicina do ABC from 2006 to 2010. Results: The median age was 58.5 years. Anemia was observed upon diagnosis in 87% of patients, hypercalcemia in 38%, and creatinine levels higher than 2 mg/dL in 19%. M protein was detected in 85.7%. The
more » ... in 85.7%. The five-year survival rate was 74.6%. Multivariate analysis showed statistical significance for Durie-Salmon staging (p = 0.037). The International Staging System and immunoglobulin type did not correlate significantly with survival of the group. Conclusion: This set of cases from a tertiary public healthcare service reflect the approach of multiple myeloma in a predominantly young population with advanced clinical staging, with results comparable to those of the literature.
doi:10.1590/s1679-45082011ao2006 pmid:26760807 fatcat:ommuzzuqarezxk4gkgdzxg62hq