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Holographic optogenetic stimulation of patterned neuronal activity for vision restoration
When natural photoreception is disrupted, as in outer-retinal degenerative diseases, artificial stimulation of surviving nerve cells offers a potential strategy for bypassing compromised neural circuits. Recently, light-sensitive proteins that photosensitize quiescent neurons have generated unprecedented opportunities for optogenetic neuronal control, inspiring early development of optical retinal prostheses. Selectively exciting large neural populations are essential for eliciting meaningfuldoi:10.1038/ncomms2500 pmid:23443537 fatcat:po4zxqlrvrgw3hqhfrqndqr7u4