Sodium dodecyl sulfate as a viral inactivator and future perspectives in the control of small ruminant lentiviruses

Ana Lídia Madeira de Sousa, Raymundo Rizaldo Pinheiro, Juscilânia Furtado Araújo, Dalva Alana Aragão de Azevedo, Renato Mesquita Peixoto, Alice Andrioli, Sabrina Tainah da Cruz Silva Bezerra, Maria Fátima da Silva Teixeira
2019 Arquivos do Instituto Biológico  
Infections by small ruminant lentiviruses (SRLVs) affect goats and sheep causing chronic multisystemic diseases that generate great economic losses. The caprine lentivirus (CLV) and the ovine lentivirus (OLV) present tropism for cells of the monocyte/macrophage lineage, which are directly associated with the main route of transmission through the ingestion of milk and colostrum from infected animals. In this manner, controlling this route is of paramount importance. Currently, researches have
more » ... , researches have investigated the use of chemical additives in milk that can preserve colostrum or milk and inactivate microbiological agents. Among the compounds, sodium dodecyl sulfate (SDS) has been shown to be satisfactory in the chemical inactivation of HIV and CLV in milk, and also as a biocide in goat colostrum.
doi:10.1590/1808-1657000752018 fatcat:mrvnwcwlgjd55ozmak3qrjtmqi