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CARVEDILOL AND NEBIVOLOL PROTECT THE KIDNEY AGAINST RENAL ISCHEMIA IN WISTAR RATS
Zagazig University Medical Journal
Classical β-blockers usually reduce renal blood flow thus, worsening renal function in hypertensive patients with renal impairment. However, vasodilator -blockers with biased agonist activity on -arrestin, at least theoretically, could protect the kidney against ischemia. Objectives: To compare the effect of prophylactic administration of carvedilol, nebivolol, nadolol on the kidneys. Materials & Methods: Rats were divided into five groups: Group1: shamoperated; Group2: Untreateddoi:10.21608/zumj.2019.30932 fatcat:rdofu2b7ffgz3jjs5mzyvzm7uu