Dengue fever is common in Southeast Asia although liver failure is a rare complication with up to 50% mortality rate reported in children. Objective: To evaluate the characteristics and treatment outcome of dengue fever associated liver failure (DFALF) in a case series of 4 paediatric patients. DFALF was defined as INR>2, regardless of the presence or absence of encephalopathy or INR>1.5 not corrected by Vitamin K in the presence of clinical hepatic encephalopathy, during the course of

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... t dengue infection. Material and methods: Patients with DFALF, admitted to a tertiary paediatric centre in Singapore over a 6 year period (January 2009-December 2015 were identified from the Gastroenterology and Infectious Disease databases. Case records were retrospectively reviewed.