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The Ultrastructural Localization of NADPH-diaphorase in the Cerebral Arteries of Rats
The Keio Journal of Medicine
The ultrastructural localization of nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d), which has been considered to be a neuronal nitric oxide synthase (NOS), was explored in the vascular endothelial cells and perivascular nerves of the cerebral arteries in the rat. In order to detect NADPH-d activity, 2-(2'-benzothiazolyl)-5-styryl-3-(4'-phthalhydrazidyl) tetrazolium chloride was utilized as a substrate for NADPH-d histochemistry at the electron microscopic level. In vasculardoi:10.2302/kjm.45.318 fatcat:g5zm3346tngzli5tfe4tiixv3q