Prosthetic joint infections are much-feared complications of joint arthroplasty that require complex multidisciplinary treatment. Although prosthesis removal is usually needed, the performance of debridement, antibiotics, and implant retention (DAIR) is an attractive alternative in well-selected patients with acute infection. Whether or not to indicate DAIR in a given situation is not a straightforward decision, despite validated algorithms and published guidelines. The odds of eradicating the

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... nfection and retaining an arthroplasty that is functional and painless are influenced by multiple variables regarding not only type of infection but also causative microorganism, antimicrobial treatment, surgical procedure, and the patient's condition and baseline characteristics. In this narrative review, we go over current recommendations, and algorithms, along with reported rates of success and risk factors of failure, and we will balance the decision to perform DAIR against other alternatives.