We report herein on our experience of a case of IgD multiple myeloma with cavernous sinus syndrome and an orbital tumor. Left blepharoptosis and left eye movement disorder were observed associated with the cavernous sinus syndrome in a 59-year-old female. The orbital tumor was biopsied using the endoscopic endonasal transparanasal technique and was diagnosed as an IgD multiple myeloma. The left blepharoptosis and left eye movement disorder recovered fully following ROAD-IN therapy. Based on our

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... experience we believe that the endoscopic endonasal transparanasal technique can be applied as an approach to orbital lesions.