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On Relationship Inference Using Gamete Identity by Descent Data
Journal of Computational Biology
Related individuals are identical by descent (IBD) at a genetic locus if they share the same DNA material from a common ancestor. Continuous gamete IBD data consist of the lengths of (in order) IBD and non-IBD regions along the genomes for gametes segregating from two related individuals and can be used to distinguish different relationships. Under the assumption that the crossovers follow a Poisson process, we show that the exact calculation of the likelihood of a particular relationship for adoi:10.1089/106652701300312940 pmid:11454305 fatcat:6gkoedzrgfg2jcg2brr3jdl7ii