Structural determination of two new acacic acid-type saponins from the stem barks of Albizia zygia (DC.) J. F. Macbr

Olivier Placide Noté, Line Made Simo, Joséphine Ngo Mbing, Dominique Guillaume, Christian Dominique Muller, Dieudonné Emmanuel Pegnyemb, Annelise Lobstein
2018 Natural Product Research  
As a continuation of our interest in the study of triterpenoid saponins from Albizia zygia, phytochemical investigation of its stem barks led to the isolation of two new oleanane-type saponins, named zygiaosides C-D (1-2). Their structures were established on the basis of extensive analysis of 1D and 2D NMR (1H-, 13C NMR, DEPT, COSY, TOCSY, ROESY, HSQC and HMBC) experiments, HRESIMS studies, and by chemical evidence as,
more » ... )]-β-d-glucopyranosyl]-21-O-[(2E,6S)-2,6dimethyl-6-O-(β-d-quinovopyranosyl) octa-2,7-dienoyl]acacic acid 28-O-α-L-arabinofuranosyl-(1→4)-[β-ᴅ-glucopyranosyl-(1→3)]-α-Lrhamnopyranosyl-(1→2)-β-d-glucopyranosyl ester (1) and 3-O-[β-dglucopyranosyl-(1→2) -[ β-d-fucopyranosyl-(1→6)]-β-d-glucopyranosyl]-21-O-[(2E,6S)-2,6-dimethyl-6-O-(β-ᴅ -quinovopyranosyl) octa-2,7-dienoyl]acacic acid 28-O-α-L-arabinofuranosyl-(1→4)-[β-dglucopyranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl ester (2). KEYWORDS 1d and 2d NMr; Albizia zygia; mimosaceae; triterpenoid saponins; acacic acid-type saponins ARTICLE HISTORY
doi:10.1080/14786419.2018.1440228 pmid:29457748 fatcat:mlqb4uynbneo7luc3d5kdjqh3m