Taxezopidine-G from needles and young stems of Taxus baccata L. growing in Iran

M Pirali-Hamedani, Verdian Rizi MR, SH Rezazadeh, R Dowlatabadi, A Hadjiakhoondi, M Amini, D Yazdani
2005 Journal of Medicinal Plants  
Taxus species are important due to their content of Taxol, baccatin III, 10- deacetyl baccatin and other taxoids suitable to change to active pharmaceutical ingredients, which are used as anti-neoplastic agents. Investigations on taxoids carried out during the past four decades, resulted in identification of more than 350 taxoids. Objective: This study aimed to isolate and identify taxoids of Taxus baccata endogenous to the north of Iran. Method: Removing of fats, extraction of components with
more » ... n organic solvent and then separation and purification of components with silica gel based column chromatography was done. Identification was carried out using NMR spectra of components. Results: Taxezopidine-G was separated and identified. Conclusion: Taxezopidine-G in Taxus baccata was isolated which had not been repoted in this spcies, previously.
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