Assessment of the extent of trauma in single-port retroperitoneal laparoscopic surgery and percutaneous nephrolithotomy treatment of upper ureteral calculi

Ji Ma
2016 Journal of Hainan Medical University  
Objective: To compare the extent of trauma between single-port retroperitoneal laparoscopic surgery and percutaneous nephrolithotomy treatment of upper ureteral calculi. Methods: A total of 118 cases of patients with upper ureteral calculi who underwent surgical treatment in our hospital from December 2013 to February 2016 were included in the study and divided into observation group and control group (n=59) according to random number table, control group received percutaneous nephrolithotomy,
more » ... s nephrolithotomy, observation group received single-port retroperitoneal laparoscopic surgery, and then differences in early postoperative inflammation, pain-related mediators, trauma-related proteins, biological effects of the pancreas and so on were compared between two groups. Results: Early postoperative WBC, CRP, PET, COR, FT3 and NE levels of observation group were lower than those of control group; pain mediators SP, IL-6, SK and NPY levels were lower than those of control group; HMGB-1 and HSP72 levels were lower than those of control group while albumin and prealbumin levels were higher than those of control group; blood amylase and urine amylase levels were lower than those of control group. Conclusion: Single-port retroperitoneal laparoscopic surgery for treatment of patients with upper ureteral calculi has positive effect on reducing surgical trauma, avoiding pancreatic trauma and other aspects, and has more clinical advantages than percutaneous nephrolithotomy
doaj:a8d2c74a2bb841b5b9d7951475df52ed fatcat:c7vfft7dobb3dmwo4b2tll2tfa