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The role of 14-3-3 proteins in cell signalling pathways and virus infection
2021
Journal of Cellular and Molecular Medicine
Preserved Fulltext
14-3-3 proteins are highly conserved in species ranging from yeast to mammals and regulate numerous signalling pathways via direct interactions with proteins carrying phosphorylated 14-3-3-binding motifs. Recent studies have shown that 14-3-3 proteins can also play a role in viral infections. This review summarizes the biological functions of 14-3-3 proteins in protein trafficking, cell-cycle control, apoptosis, autophagy and other cell signal transduction pathways, as well as the associated
doi:10.1111/jcmm.16490
pmid:33793048
fatcat:bubt2kzbo5b7nci5wp77e4sf5i