Objective:Our research was aimed at the evaluation of the ventilator-associated pneumonia (VAP) spectrum and length relation of the stay at the ICU, patient's gender and age were thereasons of discharge from the Intensive Care Unit (ICU). Study Design:Cross-sectional Research Place and Duration of Study:Research was completed in the time span of one year from April, 2015 to April, 2016 at the venue of Shifa International Hospital, Islamabad. Material and Methods:Research sample consisted of a

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... tal of 470 cases and out of the total sample 106 cases were diagnosed VAP and they spent more than 48 hours in ICU on mechanical ventilator. They presented positive tracheo- bronchial secretions culture including one of these; more than 48 – hours chest radiograph infiltrate, fever above 38.3°C, leukocytosis above 12 x 109 /ml and elevation in the tracheo-bronchial secretions which established VAP diagnosis. Results:Male and female had the mean age factor respectively 49.8±18 and 50.6±21.4 years with an average ICU stay of 16.6±13 days. Acinetobacterbaumanniwas observed in 30.2% VAP patients having colistin sensitivity of 96.8%, 27.4% cases presented Klebsiella pneumonia with the sensitivity rate of 72 and 62 percent respectively in colistin and carbapenems.Methicillin-resistant Staphylococcus aureus was observed in 15.1% patients having a rate of 100% vancomycinsensitivity. An increase of VAP late-onset incidence of 60.4% was contrasted with 39.6% in respect of an early VAP onset. VAP cases presented a 28.6% rate of mortality. Conclusion:Our research recommends colistintherapy combined with vancomycin and carbapenems in the cases of VAP. There was no significant statistical association in the ICU stay length and the rate of overall mortality of the patients. Discharge odds were 3.2 times of male cases were more than the female cases. A decrease in the factor of age was linked to the discharge factor from ICU