Neuropsychiatric Symptoms at Menopause

PK Maheshwari, Prabhat Agrawal, Prashant Prakash, Anjana Pandey, Syeda Batool Mazhar
2015 The Journal of South Asian Federation of Menopause Societies  
Neuropsychiatric symptoms, such as depression and anxiety are more frequent in women than men. Various factors, such as genetic predisposition, psychosocial vulnerability, excessive stress and somatic diseases may explain gender differences. Moreover a strong association in the precipitation of symptoms seem to be related to the female reproductive cycle: premenstrual tension syndrome, postpartum depression or climacteric depression. These indicated the influence of hormonal fluctuations on the
more » ... fluctuations on the brain. Estrogen modulates several neurotransmitters, has direct effect on neurons by stimulating axonal sprouting, including vasodilatation. These findings lead to the theory that neuropsychiatric symptoms at menopause may be associated with declining estrogen levels and hormone therapy may help in appropriate cases. HORMONE THERAPY (HT) AND MOOD Dementia is a chronic of cognitive abilities and result in prominent changes and personality and ultimately there is deterioration in a person's physical and neurological status. Hence, dementia is a debilitating illness affecting memory and cognition, behavior personality traits level of independence, physical and neurological function. 1 Dementia can be considered as 'chronic brain failure' and delirium is associated with reduced attention or consciousness. Epidemiology Dementia is a common but not in evitable consequence of aging. Its prevalence and incidence increase with age
doi:10.5005/jp-journals-10032-1071 fatcat:ez5u5luglrg3zhzjlzqzredrny