Genetics of schizophrenia: communicating scientific findings in the clinical setting

JL Roos
2011 African Journal of Psychiatry  
The expected identification of susceptibility genes for psychiatric disorders may bring new opportunities and expectations from patients and families for the clinical translation of research findings in psychiatric genetics. In this article information is provided about familial risk of schizophrenia with the theory behind individualizing risk of recurrence highlighted. Recent new findings regarding the new genetic frontier, Copy Number Variations (CNV), are summarized and the genetic
more » ... e genetic architecture of familial and sporadic schizophrenia applicable to the clinical situation is reviewed. A scenario in which genetic testing could be applied in velocardiofacial syndrome (VCFS) type schizophrenia is debated. Referring to genetic discrimination in mental disorders, reference is made
doi:10.4314/ajpsy.v14i2.1 fatcat:tt3xvqunnnbebdjpmcydhdtjfe