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Exact computational analyses for adaptive designs
[chapter]
1995
Lecture Notes-Monograph Series
Preserved Fulltext
We show h o w to compute optimal designs and exact analyses of allocation rules for various sequential allocation problems. The problems we h a ve solved include parameter estimation in an industrial scenario, and testing in a clinical trial. Our computational approach incorporates backward induction, dynamic programming, and a new technique of forward induction. By utilizing e cient algorithms and careful implementation, we are able to determine exact solutions to practical problems previously
doi:10.1214/lnms/1215451488
fatcat:rc26mmphkfaovdorw25pxtgrge