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Glutathione S-transferase M1, T1, and P1 polymorphisms and survival among lung cancer patients
2003
Cancer Epidemiology, Biomarkers and Prevention
Glutathione S-transferase (GST) enzymes detoxify therapeutic drugs and reactive oxidants, so GST polymorphisms may influence survival after diagnosis of cancer. We evaluated survival according to GST polymorphisms in a population-based series of lung cancer patients. The study subjects (n = 274) were men diagnosed with lung cancer from 1993 through 1996 who participated in a case control study and provided a blood sample for genotyping. The presence of the GSTM1 and GSTT1 genes were assayed by
pmid:12814998
fatcat:223o6y45ivcvrj3lupwwtz6q3a