Investigation of Viral and Atypical Pathogens in Patients with Pneumonia Who Need Intensive Care Unit
Yoğun Bakım Gerektiren Pnömonili Hastalarda Viral ve Atipik Patojenlerin Araştırılması

Ahmet Doğan, Yasemin Ersoy Çınar, Barış Otlu, Çiğdem Kuzucu
2022 Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi  
Viral pathogens have been reported increasingly in pneumonia patients. There are few studies in Turkey on viral and atypical bacterial etiology in adult patients with community-acquired pneumonia (CAP) or hospital-acquired pneumonia (HAP). In this study, it was aimed to determine atypical and viral pathogens in patients with pneumonia requiring ICU and to research clinical progression. Materials and Methods: Adult patients admitted to adult ICUs between November 2016-October 2017 with either
more » ... or HAP diagnosis were included prospectively. Viral pathogens and also atypical bacterial pathogens were investigated with the in-house multiplex polymerase chain reaction method. Results: Two hundred patients were enrolled to the study, of whom 63 had CAP (31.5%) and 137 had HAP (68.5%). Viral agents were identified in 31 (15.5%) patients in total, 11 (17.5%) in CAP and 20 (14.6%) in HAP. The most identified viral etiologic agents were rhinovirus, influenza A, and coronavirus HKU. Eight patients (4%) had Mycoplasma pneumoniae. All patients were negative for Legionella pneumoniae and Chlamydophila pneumoniae. Mortality rates were 16.7% for cases with a viral etiology only, 29.2% for cases with bacterial pathogens only, and 23.5% for cases with mixed agents identified. Conclusion: Viral pathogens and M. pneumoniae should be remembered in the etiology of severe pneumonia patients.
doi:10.5578/flora.20229903 fatcat:urearh5znrgvdeezlfwyfxjari