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The Role of Cytotoxic Therapy with Hematopoietic Stem Cell Transplantation in the Treatment of Adult Acute Lymphoblastic Leukemia: Update of the 2006 Evidence-Based Review
Biology of Blood and Marrow Transplantation
Clinical research published since the first evidence-based review on the role of hematopoietic stem cell transplantation (SCT) in the treatment of acute lymphoblastic leukemia (ALL) in adults is presented and critically evaluated in this update. Treatment recommendations changed or modified based on new evidence include: (1) myeloablative allogeneic SCT is an appropriate treatment for adult (\35 years) ALL in first complete remission for all disease risk groups; and (2) reduced-intensitydoi:10.1016/j.bbmt.2011.07.019 pmid:21963620 fatcat:wedtg2h7nrcn3lsucwqenytbsi