In the initial evaluation of breast lumps, Fine Needle Aspiration (FNA) is a proven diagnostic technique. Aim of the study is to grade the infiltrating ductal carcinoma of breast by both cytologically and histologically and to correlate its grading. A total of 44 cases with a cytological diagnosis of invasive ductal carcinoma subsequently proved on histology were studied. These were graded according to Robinson's cytological grading (RCG) and Elston's modification of Bloom Richardson's

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... cal grading system. Statistical analysis was done using χ 2 test. Multiple regression analysis was done to assess the significance of each cytological and histological parameter. There were 22(50%), 19(43.1%) and 3(6.8%) cases of grade I, II and III ductal carcinomas respectively graded cytologically and 19(43.2%), 20(45.5%) and 5(11.4%) cases of ductal carcinomas graded I, II and III histologically. Overall, in 37 cases (84%) the cytological grade correlated with the histological grade and in 7 cases (18%) discrepancy was noted. There was a significant association (p<0.05) between the cytological and histological grading. This study showed that the extent of cell size, cell uniformity, nucleoli were the most influential features. 68% of grade I tumors 53% of grade II and 100% of grade III tumors showed lymphnode metastasis. Lymph node metastasis was seen irrespective of the grade of the tumor. To conclude grading act as powerful predictor of tumor aggressiveness; should thus be addressed in pathological analysis of breast carcinoma as it is simple and feasible.