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The Protective Effect of Adalimumab on Intestinal Injury induced with Infrarenal Aortic Occlusion
İnfrarenal aort oklüzyonu ile oluşan intestinal hasarında adalimumab'ın koruyucu etkisi
2019
Turkish Journal of Trauma and Emergency Surgery
İnfrarenal aort oklüzyonu ile oluşan intestinal hasarında adalimumab'ın koruyucu etkisi
The present study aims to observe the effects of ischemia-reperfusion (IR) on small intestines at a molecular level and to prospectively assess the potential preventive role of adalimumab (ADA) and antioxidants. A total of 24 male Sprague-Dawley rats were randomly divided into three groups-a control group, an IR group and an IR+ADA group. Although there was no change in SOD levels in the small bowel tissue of the IR group, we observed increased malondialdehyde (MDA) levels and increased
doi:10.14744/tjtes.2019.59607
pmid:32436975
fatcat:5sqknxou4fhsjjpxf4aaqaoa2m