Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales

Sylvia S Grierson, Dirk Werling, Cornelia Bidewell, Susanna Williamson
2017 The Veterinary Record  
This is the peer-reviewed, manuscript version of an article published in Veterinary Record. The final version is available online via http://dx. ABSTRACT Confirmed cases of porcine circovirus disease (PCVD) in GB have shown a steady decline since the availability of porcine circovirus 2 (PCV2) vaccines. However, PCVD is still sporadically diagnosed. We carried out a genotyping study to characterise PCV2 associated with confirmed PCVD cases in England and Wales from 2011 to January 2016 (n=65).
more » ... nuary 2016 (n=65). A partial fragment of PCV2 genome encompassing open reading frame 2 (ORF2) was amplified and sequenced from 45 cases of PCVD. The majority of sequences were genotype PCV2b but four sequences were PCV2d. The significance of the emergence of PCV2d in England and elsewhere in the world is not yet known but may represent a global genotype shift.
doi:10.1136/vr.104450 pmid:29051314 fatcat:atkniop74vbx5mpcqrrgd7mm7i