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Topical tacrolimus therapy of resistant cutaneous lesions in lupus erythematosus: a possible alternative
Objective. To determine the efficacy of tacrolimus ointment 0.1% on resistant cutaneous lesions in patients with lupus erythematosus. Methods. Twelve patients with skin manifestations were studied. Six had discoid lupus (DL), four subacute cutaneous lupus erythematosus (SCLE) and two systemic lupus erythematosus (SLE). All patients had extensive skin lesions refractory to previous treatment. Patients received topical tacrolimus 0.1% for a minimum of 6 weeks and response was evaluated bydoi:10.1093/rheumatology/keh325 pmid:15266063 fatcat:y3abpo2czfbjvh2m44zt2vyxre