Fatty Acid Composition and Anti-inflammatory Effects of the Freeze Dried Tenebrio molitor Larva
동결건조 갈색거저리 유충의 지방산 조성과 항염증 효과

Mi-Sook Kang, Min Ju Kim, Jung-Soon Han, Ae-Jung Kim
2017 The Korean Journal of Food And Nutrition  
This study aimed to assess fatty acid composition and anti-inflammatory effects, such as nitric oxide(NO) production, expression of TNF-α and interleukin-6(IL-6), of Tenebrio molitor larva using RAW 264.7 cells. The content of total fatty acid in Tenebrio molitor larva was 76.14%, which was composed of oleic acid(42.12%), linoleic acid(32.67%) etc. There was no cytotoxicity at a dose level of 0.1, 1.0, 10, and 100 μg/mL of freeze dried Tenebrio molitor larva ethanol extract(FDTEtOH) on RAW
more » ... DTEtOH) on RAW 264.7 cells. FDTEtOH significantly decreased NO production in LPS(lipopolysaccharide)stimulated RAW 264.7 cells in a dose-dependent manner. Also, FDTEtOH dose-dependently suppressed the expression of TNFα and IL-6. Thus, these results showed that Tenebrio molitor larva has the potential to be used as an anti-inflammatory food to improve immunity.
doi:10.9799/ksfan.2017.30.2.251 fatcat:ilporc2j25dj5fczmyurimnu7a