Since the incidence of post-cricoid carcinoma is low among all of the hypopharyngeal carcinoma in Japan, the number of informative reports on this cancer is relatively small. We had experienced 25 cases of postcricoid carcinoma patients who underwent initial treatment in our hospital ⊖ the National Cancer Center Hospital East ⊖ from 2007 to 2012. Five cases of superficial carcinoma patients who underwent endoscopic mucosal resection had good clinical courses. We concluded that endoscopic

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... could be appropriate for superficial post-cricoid carcinoma. The other 20 cases of locally advanced carcinoma underwent surgery or chemo/radiotherapy. Although each treatment group had similar outcomes, the larynx preservation rate of the non-operative treatment group was as low as 23%. Salvage surgery after chemo/radiotherapy for a residual or recurrent tumor could be a choice ; however, we should determine the treatment strategy with consideration of tumor progression stage or general condition. : hypopharynx cancer, post-cricoid, head and neck