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Bio-inspired materials for parsing matrix physicochemical control of cell migration: A Review
2012
Integrative Biology
Cell motility is ubiquitous in both normal and pathophysiological processes. It is a complex biophysical response elicited via the integration of diverse extracellular physicochemical cues. The extracellular matrix directs cell motility via gradients in morphogens (a.k.a. chemotaxis), adhesive proteins (haptotaxis), and stiffness (durotaxis). Three-dimensional geometrical and proteolytic cues also constitute key regulators of motility. Therefore, cells process a variety of physicochemical
doi:10.1039/c1ib00069a
pmid:22025169
fatcat:yizpmcllk5g3tokr2h2vhqn4k4