ACTA REUMATOLÓGICA PORTUGUESA NÃODEKA-C2DEA OSTEOPOROSE ACABE COM OS iifiSlCCrt Calcitonina sintética de salmão

Vol Xxiii, Regina Cleanora, Oficial Órgão, Sociedade Da, Reumatologia De, Rat^at
1998 unpublished
Some patients with inflammatory bowel disease (IBD) have reduced bone mineral density (BMD). The aim of the present study was to correlate BMD and risk factors such as age, disease duration and severity. Methods: We studied 25 patients with IBD, 15 with Crohn's disease, 10 with Ulcerative colitis. BMD of the radio was measured using dual-energy X-ray absorptiometry. The BMD of the radio expressed as proximal and distal T-score, identified 7 and 5 cases of osteopenia, and 2 and 0 cases of
more » ... d 0 cases of osteoporosis, respectively. We found no correlation between BMD and risk factors. The prevalence of reduced BMD is increased in patients with IBD, as found in others series. The compromise of young patients, without others risk factors, emphasises the need for effective prophylatic measures. Abstract: Osteoporosis and bone formation are simultaneous conditions in ankylosing spondylitis (AS). Reduced bone mass is a potencial contributor to increased prevalence of vertebral fractures, in these patients. Low mineral mass was diagnosed in axial but not in peripheral skeleton, and begins early in the course of the disease. The exact cause of osteopenia in AS remains to be determined, but may be multi-factorial. Potencial factors are spine immobility, inflammatory process, genetic factors, hormonal modifications and the chronic use of non-steroidal anti-inflammatory drugs. Calcium-phosphoro homeostasia seems to be normal although some studies show conflitings results.
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