Reproductive Hormone Profiles and Their Relationships with Sexual Function in Patients with Prostate Cancer after Rapid Prostatectomy in Benin City

Babatunde Ishola Gabriel Adejumo, Omolei Lilian Williams, Efosa Bolaji Odigie, Ifeoma Gloria Unachukwu, Oladimeji Nasiru Abdulrahman, Uchechukwu Dimkpa, Simon Uzor, Oyarazi Margaret Adebowale, Ojo Moses Oke
2020 Advances in Sexual Medicine  
There are limited studies examining the relationship between serum reproductive hormone levels and sexual functions among prostate cancer (PCa) patients after rapid prostatectomy (RP). Aim: The present study aimed at evaluating the correlation between post-operative serum levels of some male reproductive hormones of PCa patients and their sexual functions in the months following RP. A total of 20 male patients with clinically localized PCa who had undergone RP within the last 12 months prior to
more » ... commencement of the study, were invited to participate. The postoperative serum levels of their luteinizing hormone (LH), follicle stimulating hormone (FSH) and total testosterone (Te) were measured. They also completed a structured health and lifestyle questionnaire to obtain information on their demographic characteristics and detailed medical history. Our data indicated normal mean levels of post-operative Te (4.34 ± 4.38 ng/ml) in the patients following RP, while the mean levels of FSH (39.24 ± 34.12 miu/ml) and LH (21.67 ± 25.73 miu/ml) were on the increase and far above normal ranges for healthy men. Data indicated a significant positive correlation between Te and frequency of sexual intercourse (r = 508; p < 0.05), libido (r = 0.429; p < 0.05) and penile erection (r = 0.494; p < 0.05). However, no significant correlations were found between FSH or LH and any of the sexual function parameters. The present
doi:10.4236/asm.2020.104008 fatcat:axxxays6djcjhi47ptwy6f2rta