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Mussel defensins are synthesised and processed in granulocytes then released into the plasma after bacterial challenge
1999
Journal of Cell Science
MGD1 (Mytilus galloprovincialis defensin 1), a new member of the arthropod defensin family, is a 4 kDa antibacterial peptide previously isolated from the plasma of Mediterranean mussels. We report here the presence of MGD1 in the organelle-rich fraction of hemocytes and the cDNA sequence corresponding to MGD1 and one new isoform mRNA: MGD2. Sequence analysis indicated that MGDs are synthesised as precursors consisting of a putative signal peptide of 21 residues, the active peptide of 39 amino
pmid:10564642
fatcat:obhxvb4k4beqlbd6vcckfw73iq