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The efficacy of combined β-Propiolactone/Ultraviolet irradiation (βPL/UV) for inactivation of hepatitis B virus in labile blood derivitives has been reinvestigated. To permit quantitative estimation of process efficacy, a regression analysis of the relation between virus dose and incubation period was carried out. This has provided a means for estimating virus titer and for determining the accuracy of such estimates.The data suggest that βPL/UV can reduce virus titer about 10,000,000 folddoi:10.1055/s-0038-1652315 fatcat:47cbuggz6bgx5m7r74loblolci