A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf
.
The in silico macrophage: toward a better understanding of inflammatory disease
2011
Genome Medicine
Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs within the macrophage enable such functional diversity. To investigate how programs of gene expression relate to the phenotypic attributes of the macrophage, the development of in silico modeling methods is needed. Such models need to cover
doi:10.1186/gm218
pmid:21349141
pmcid:PMC3092089
fatcat:z2sjufkuy5fu5dw3kkzzjmyrfq