Objectives: identify levels of uncertainty, as well as determine the relationship and effect of uncertainty and perceived stress with the psychological wellbeing of the main family member of the person dependent on alcohol. Methodology: correlational and transversal quantitative study, the sample consisted of 135 family women of people dependent on alcohol, the instruments used were the Scale of Perception of Uncertainty in Parents and Family Members (PPUS-FM) of Mishel and the Scale of

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... d Stress (PSS), which was designed by Cohen, et al. Results: the total of the participants reported uncertainty, the high uncertainty level predominated Incertidumbre, estrés y su relación con el bienestar psicológico en familiares de dependientes del alcohol Uncertainty, stress and its relationship with psychological well-being in family members of alcohol dependents Incerteza, estresse e sua relação com o bem-estar psicológico em familiares de dependentes de álcool