A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf
.
Agent-Based Modeling in Systems Pharmacology
2015
CPT: Pharmacometrics & Systems Pharmacology
Modeling and simulation (M&S) techniques provide a platform for knowledge integration and hypothesis testing to gain insights into biological systems that would not be possible a priori. Agent-based modeling (ABM) is an M&S technique that focuses on describing individual components rather than homogenous populations. This tutorial introduces ABM to systems pharmacologists, using relevant case studies to highlight how ABM-specific strengths have yielded success in the area of preclinical mechanistic modeling.
doi:10.1002/psp4.12018
pmid:26783498
pmcid:PMC4716580
fatcat:kf7lhaq7hbcb3li5queac5yjam