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PRKCA overexpression is frequent in young oral tongue squamous cell carcinoma patients and is associated with poor prognosis
[article]
2020
medRxiv
pre-print
Oral tongue squamous cell carcinoma (OTSCC) have an increasing incidence in young patients and many have an aggressive course of disease. The molecular mechanisms for this increase are unknown and biologic markers to identify high risk patients are lacking. In an unbiased data screening for differential protein expression of younger (≤45 years) and older (>45 years) OTSCC patients in The Cancer Genome Atlas (TCGA) cohort (n=98) we identified Protein kinase C alpha (PRKCA), to be significantly
doi:10.1101/2020.06.21.20122648
fatcat:hqmgd7i35jdptmiyic5463nemq