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This paper presents the influence of the ratio IA/PA and concentration of volatile acids (TVA) in the operational stability of a UASB reactor treating swine waste water. The treatment system in real scale was constituted of decanter, followed by the UASB reactor with volume of 7.4 m 3 and 11.5 m 3 , respectively. It has been observed a large oscillation of the ratio IA/IP in the UASB reactor with an average value of 0.39, and average efficiency of removal of BOD and COD of 79.8 and 79.3%,doi:10.4236/jwarp.2014.65051 fatcat:7qrck5ei55fqjinicuonjvrmpy