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Many questions about the dependence of age-appropriate pathological changes of the skin on background malassezia destruction require clarifi cation and further advance. Aim. In 90 patients with involutive changes in facial skin, including 60 patients with malasseziasis, determination of the state of the epidermis was carried out using electron microscopy. Methods and results. It was found that in 33-40 years old patients leading violation of facial skin is hyperkeratosis. In the age group ofdoi:10.14739/2310-1237.2015.1.42935 fatcat:hkcxfi3mhbhzjjm3jv5x6zky4q