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Identification and molecular cloning of novel antimicrobial peptides from skin secretions of the Chinese bamboo leaf odorous frog ( Odorrana versabilis ) and the North American pickerel frog ( Rana palustris )
2017
Journal of Traditional Chinese Medical Sciences
Objective: Amphibian skin secretions are an abundant source of bioactive peptides, some of which could be developed as candidate drugs. Among these natural peptides, cytolytic peptides have attracted the most attention given that they might replace conventional antibiotics and help deal with the problem of microbial resistance. This study discovered two bioactive peptides, Brevinin-1-PLr and Nigrocin-2-OV, from two species frogs, Rana palustris and Odorrana versabilis, respectively. Their
doi:10.1016/j.jtcms.2017.07.007
fatcat:67hzficnm5ag5ogzavbv6raahy