A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is
TIGR Assembler: A New Tool for Assembling Large Shotgun Sequencing Projects
Genome Science and Technology
A new approach to assembling large, random shotgun sequencing projects has been developed. The TIGR Assembler overcomes several major obstacles to assembling such projects: the large number of pairwise comparisons required, the presence of repeat regions, chimeras introduced in the cloning process, and sequencing errors. A fast initial comparison of fragments based on oligonucleotide content is used to eliminate the need for a more sensitive comparison between most fragment pairs, thus greatlydoi:10.1089/gst.1995.1.9 fatcat:xnsvi7qfezd3nnct226p6bcmzq