Association of cannabis use with prodromal symptoms of psychosis in adolescence

Jouko Miettunen, Sari Törmänen, Graham K. Murray, Peter B. Jones, Pirjo Mäki, Hanna Ebeling, Irma Moilanen, Anja Taanila, Markus Heinimaa, Matti Joukamaa, Juha Veijola
2008 British Journal of Psychiatry  
Recent interest has focused on the association between cannabis use and risk of psychosis. In the largest unselected population-based study on this topic to date, we examined cannabis use and prodromal symptoms of psychosis at age 15-16 years among 6330 adolescents. Those who had tried cannabis (n=352; 5.6% of the total sample) were more likely to present three or more prodromal symptoms even after controlling for confounders including previous behavioural symptoms (OR=2.23; 95% CI 1.70-2.94).
more » ... dose-response effect was seen. We conclude that cannabis use is associated with prodromal symptoms of psychosis in adolescence.
doi:10.1192/bjp.bp.107.045740 pmid:18515902 fatcat:fwov3on66zai7n2vsr3slsnzsy