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Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes
2002
Annual Review of Biochemistry
f Abstract DNA repair is crucial to the well-being of all organisms from unicellular life forms to humans. A rich tapestry of mechanistic studies on DNA repair has emerged thanks to the recent discovery of Y-family DNA polymerases. Many Y-family members carry out aberrant DNA synthesis-poor replication accuracy, the favored formation of non-Watson-Crick base pairs, efficient mismatch extension, and most importantly, an ability to replicate through DNA damage. This review is devoted primarily to
doi:10.1146/annurev.biochem.71.083101.124707
pmid:12045089
fatcat:a7panflzifb3rlk4tphx7o3miq