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New approaches for reconstructing phylogenies from gene order data
2001
Bioinformatics
We report on new techniques we have developed for reconstructing phylogenies on whole genomes. Our mathematical techniques include new polynomial-time methods for bounding the inversion length of a candidate tree and new polynomial-time methods for estimating genomic distances which greatly improve the accuracy of neighbor-joining analyses. We demonstrate the power of these techniques through an extensive performance study based on simulating genome evolution under a wide range of model
doi:10.1093/bioinformatics/17.suppl_1.s165
pmid:11473006
fatcat:k3tkrhnmcbctnlbf2nkfua3sdq