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Blind recovery of biochemical markers of brain cancer in MRSI
2004
Medical Imaging 2004: Image Processing
We present an algorithm for blindly recovering constituent source spectra from magnetic resonance spectroscopic imaging (MRSI) of human brain. The algorithm is based on the non-negative matrix factorization (NMF) algorithm, 1, 2 extending it to include a constraint on the positivity of the amplitudes of the recovered spectra and mixing matrices. This positivity constraint enables recovery of physically meaningful spectra even in the presence of noise that causes a significant number of the
doi:10.1117/12.534652
dblp:conf/miip/DuMSS04
fatcat:q3owuqkmova57atzrqn7nsfy5i